Lukijakyssä: Insuliini ja lihaskasvu

Tarvitaako sitä insuliini nostaa erittäin korkealla treenin jälkeen jotta lihaksen kasvaa kunnolla? Voinko ottaa vaikka pelkkää heraproteiinia joka sekin kait lisää insuliinin erityistä?

Insuliinilla on antikatabolinen ja lihasglykogeenin synteesiä stimuloiva vaikutus, mutta sen rooli proteiinisynteesin stimuloinnissa ei ole selvä. Lainaan alle lyhyen pätkän tekeillä olevasta artikkelistani:

"However, a growing body of evidence suggest that insulin is simply permissive for muscle protein anabolism. For example, Greenhaff et al. demonstrated that hyperaminoacidemia does not require hyperinsulinemia to exert a power anabolic effect in human skeletal muscle. Specifically, they showed that increasing availability of amino acids and of insulin over the range of 5–167 mU/l doubled leg protein synthesis and halved leg protein breakdown without any dose-response relationship with insulin. In other words, hyperaminoacidemia has powerful anabolic effects even in face of basal insulin (~5 mU/l).

More practical evidence was provided by Koopman et al., who showed that co-ingestion of high-glycemic carbohydrates during recovery does not further stimulate post-exercise muscle protein anabolism when a relatively large amount of casein protein hydrolysate is ingested eventhough plasma insulin responses were markedly enhanced by carbohydrates. Also, Harber et al., reported that a high-protein/very-low-carbohydrate diet increases skeletal muscle protein anabolism despite a dramatic reduction in insulin levels. Thus, it now appears that insulin is mainly permissive rather than stimulatory for muscle protein anabolism. However, more research in this area is needed before firm conclusion can de drawn."